At Supreme Factory, we believe that longevity is the ultimate ROHI (Return On Health Investment). But you cannot optimize what you do not recover. While most founders and high-performers focus on the “hustle,” the most elite biohack for cognitive edge and physical durability isn’t found in a pill or a cold plunge – it’s found in your bedroom.
I, Prem Sangeet, recently sat down with Olivia Arezzolo, the world-renowned “Sleep Queen” and author of Bear, Lion, and Wolf, on The Elementis Way podcast. We explored why sleep is the fundamental infrastructure of the glymphatic system and how you can engineered your environment for peak longevity, while siping Okeara structured hydrogen water.
The Biological Cost of “Getting By”
We often treat sleep as a negotiable asset, but the data Olivia shared suggests otherwise. Consistently sleeping only 6 hours isn’t just a productivity killer; it’s a physiological threat. Large-scale studies involving nearly 500,000 participants show that this level of deprivation:
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Increases heart attack risk by 48%
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Increases dementia risk by 30%
Even a single night of 4–6 hours of sleep triggers a 40% spike in inflammatory biomarkers like C-reactive protein. At Supreme Factory, we focus on reducing systemic inflammation to extend the human healthspan—and it starts with the pillow.
The Brain’s “Washing Machine”: The Glymphatic System
One of the most vital takeaways for any high-performer is the role of the glymphatic system. Unlike the rest of your body, the brain lacks a traditional lymphatic system. Instead, it relies on deep sleep to open channels that “wash away” neurotoxins like beta-amyloid.
When you skip sleep, these toxins accumulate, leading to “brain fog” and a documented 29% decline in productivity the following day. Essentially, without deep sleep, your brain is operating in its own metabolic waste.
Engineering Your Circadian Sleep Sanctuary
Olivia’s protocol for a “Circadian Sleep Sanctuary” aligns perfectly with our biohacking philosophy. To optimize your internal clock, you must master these three “Zitgebers” (time-givers):
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Circadian Lighting: Evening blue light suppresses melatonin by up to 58%. Use blue-light-blocking tech or red-spectrum lighting to signal to your brain that the day is over.
Read the research paper on “The AI of Visual Wellbeing” by State On Demand -
Thermal Optimization: Melatonin production requires a drop in core body temperature. The gold standard for sleep induction is a room kept at 18°C (64°F).
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Sensory Anchors: Lavender has been shown to reduce anxiety by 45% (comparable to pharmaceutical sedatives), while white noise or water sounds can help you reach sleep states 42% faster by synchronizing brain waves.
Read the research paper on “The Neuroscience of Sound” by State On Demand
Find out more the rise of sleep industry my latest published report “Wellness Nexus“ combining the science of Longevity, the rise of Wellness Real Estate, and the evolution of Wellness Tourism.
DNA-Driven Rest: What is Your Chronotype?
Biohacking is never one-size-fits-all. Olivia highlights the importance of Chronotypes—your genetically imprinted sleep-wake cycle:
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Lions: The early-morning powerhouses.
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Wolves: The evening creatives and night-owl founders.
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Bears: The steady majority who follow the solar cycle.
When you align your deepest work with your biological peak and your rest with your natural dip, you stop fighting your DNA and start leveraging it.
The Supreme Sleep Kit
To begin your optimization journey today, Olivia recommends these three non-negotiables:
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Blue Light Blocking Glasses: Critical for protecting melatonin during evening screen time.
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Magnesium Glycinate: The essential mineral for neuromuscular relaxation and stress mitigation.
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Silk Eye Mask: Ensures total darkness to prevent any disruption to your circadian rhythm.
These tools create a biological “off-switch” that allows your nervous system to transition from high-stakes output to deep, restorative repair. Make sure to check out some of Supreme Factory portfolio companies like Orca by hangAIR™, a patented smart incliner designed by doctors and scientists, supported by wellness App, to help the 3 billion people worldwide who suffer from back pain, sleep deprivation, respiratory problems, mental stress and anxiety.
Join the Longevity Movement
Sleep is the cornerstone of the Elementis philosophy. If you are ready to move beyond “standard” health and into the realm of elite longevity, we invite you to take the next step.
Join the Longevity Club — an exclusive community of founders, biohackers, and health visionaries. Gain access to our private retreats, advanced protocols, and a network dedicated to mastering the art of living longer and performing better.
